Anti-parasitic drugs should always be administered to goats orally, even if a pour-on or injectable product is used. Single and multi-dose drench guns are available for administering oral medications to sheep and goats. You can restrain the animal by straddling it or standing beside it and placing your hand under its jaw. The syringe should be inserted into the corner of the animal's mouth and rested on its tongue. The plunger should be slowly pushed so that the medicine goes over the tongue. Once the animal has swallowed the syringe can be released. Care should be taken not to underdose animals. Weight should be obtained using a scale or tape measure to assure proper dosage. Underdosing leads to drug resistance.

Drug families should be rotated on an annual basis to slow the rate of drug resistance. There are three families of drugs which have been used to treat sheep and goats for internal parasites. They are the Benzimidazoles (white dewormers) - Fenbendazole (SafeGuard/Panacur), Albendazole (Valbazen), and Oxybendazole (Synanthic); the Nicotinics - Levamisole (Tramisol/Levasol), Pyrantel (Strongid), and Moratel (Rumatel); and the Macrolytic Lactones or Avermectins - Ivermectin (Ivomec), Doramectin (Dectomax), and Moxidectin (Cydectin/Quest). Only Fenbendazole and Rumatel are FDA-approved for use in goats. Ivomec drench, Valbazen, and Levamisol are approved for use in sheep.